I am interested in the genetic basis and evolution of complex traits. In particular, I am trying to understand how variation at the genetic and developmental levels results in variation (or lack of it) at the phenotypic level; and also, what are the consequences of such genotype-phenotype map(s) in an evolutionary context.
I’ve been exploring this broad question using the house mouse as model organism, and craniofacial shape as model phenotype. To link genetics and genomics with morphology I use mapping approaches (GWAS) and 3D geometric morphometrics. Recently, I’m doing some traditional knockout studies, coupled with gene expression analysis, with the aim of exploring, mechanistically, the determination of craniofacial shape variation.
* I will soon be moving to the US to start a postdoc in the Lab of Julien Ayroles at the Lewis-Sigler Institute for Integrative Genomics at Princeton University.